pentobarbital decreases levels of ponatinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Stay away from or Use Alternate Drug. Stay away from Except the coadministration outweighs the attainable risk of ponatinib underexposure; check for indications of lessened efficacy.fentanyl transmucosal and pentobarbital both raise sedation. Avo… Read More